What Is Generic Cialis?
Generic Cialis medicine has a high efficiency which not only improves erectile functioning, but also allows a patient to restore natural sexual relations. Cialis is safe, effective, convenient for use and secure. It restores normal sexual life for men suffering from erectile dysfunction and releases them from constant thoughts about therapy procedure.
Is Cialis a Stimulant?
First of all: NO – Cialis is NOT a sexual stimulant. In order to achieve a successful result, one should feel sexual excitement. Everything happens naturally. Cialis takes its action the very moment when it is important and never occurs when the partner is not ready for coitus.
Cialis takes positive action on the following manifestations and effects of erectile dysfunction:
- Erection in a whole;
- Possibility to achieve fully-realized erection sufficient for sexual intercourse;
- Satisfaction with sexual intercourse;
- Positive emotions;
- Self-confidence resulting from good erection;
- Confidence in achievement and preserving of erection;
- Satisfaction of a partner from coitus.
What Is the Mechanism of Generic Cialis Action?
Generic Cialis is a reversible inhibitor selectively affecting phosphodiesterase type 5. Central role in erection is played by cells relaxation of unstriated muscles of penis cavernous bodies which is locally initiated by acetylcholine and nitrogen oxide as well as other physiological agents. Acetylcholine is produced by neurons of parasympathetic nervous system, whereas nitrogen oxide is released by non-noradrenergic, non-cholinergic transmitters and endothelium cells. The net effect is inhibiting of condition of sympathetic nervous system or alpha stimulation which causes contraction of smooth muscle cells. Guanosine monophosphate and PDE5 play an important role for normal erection. Guanosine monophosphate causes arteries dilatation resulting in blood flow in cavernous bodies. Blood vessels in cavernous bodies are filled with blood causing decrease of blood outflux from penis and creation of blood pressure gradient and erection occurs. PDE5 causes decrease of guanosine monophosphate level and stops erection. Cialis inhibits PDE5 action and thus, detains the guanosine monophosphate level drop. As a result, the level of guanosine monophosphate in cavernous bodies allows a man with erectile dysfunction to have normal steady erection.
Generic Cialis Efficiency
Cialis is taken as the case may require up to once a day. It improves erection of most men suffering from erectile dysfunction of any severity degree. The clinical trials have shown that 81% of patients taking Cialis in tableted form containing 20mg improved erectile functioning. This research study included patients with different severity level of erectile dysfunction from weak form to severe one.
Generic Cialis Use
Some men feel Cialis effect in 16 minutes. For the majority of patients, the onset time is about 30 minutes. It should be borne in mind that Cialis cannot cause spontaneous erections, and it takes its effect only along with sexual stimulation. Cialis effect lasts around 36 hours. Cialis recommended dosage is 20mg. Maximum frequency of intake is once a day.
Why Generic Cialis Cannot Cause Spontaneous Erections and Other Myths about It
For a man, it is hard to consult a doctor and tell his friends about his sexual issues. The information is compiled in men’s magazines, on websites, various forums and other sources for the sake of confidentiality. That is why problems of erectile dysfunction and their solutions have produced so many myths. The recommendations are not always given by specialists; fraudulent information is spread very fast, it continues inspiring men’s confidence and elicits a smile of experts. Very often a pharmacist has to refute these rumors if a buyer doesn’t have scruples to ask this delicate question.
Myth 1: Impotency will last forever
Potency issues may be connected with various psychogenic and organic problems, such as stresses, high pressure rhythm of life, inferiority complex, chronic diseases of internal organs. But in 99% of cases the problem may be solved. Cialis was specially designed to ED treatment. This is an effective remedy curing erectile disorders in men at any age group (over 18 years of age). Cialis’s active substance is tadalafil, an efficient PDE5 inhibitor. It causes enhanced blood supply to penis and enables men to have a successful sexual intercourse.
Myth 2: Tablet is valid only for one coitus
Cialis is one of the most popular medications for erectile dysfunction, since it has a prolonged action. In Europe Cialis was called “a tablet for weekend”: its action starts in 16 minutes after fasted intake and lasts 36 hours and more (individually). A man may rest assured that from the moment of Cialis intake and within the following thirty-six hours he won’t have any problems on condition that sexual stimulation is available.
Myth 3: After Cialis intake erection is endless which is not quite comfortable
Cialis takes its action only along with sexual stimulation which causes further excitement. The medicine enhances a relaxing effect of nitrogen oxide in smooth muscle cells of penis cavernous bodies resulting in their filling with blood and erection occurrence. Natural processes are quite effective and involuntary or unwanted erection is not possible.
Myth 4: Medicines for erection achievement have many counter-indications
Cialis is a modern medicine with high profile of safety. With its help, treatment of ED became accessible for most men including those who have serious diseases, such as diabetes, atherosclerotic cardiovascular disease, adenoma, prostate carcinoma, etc. Absolute contraindications to Cialis intake are idiosyncrasy to its components and age under 18 years. Anyway, it should be taken into account that Cialis is incompatible with medicines containing any organic nitrates. Also, patients should be very careful if they use alpha blockers for hypertension or cardio-vascular diseases treatment.
Myth 5: Cialis is an expensive medicine, although in actual fact all ED drugs are similar.
Original Cialis has passed all clinical trials and has proven effectiveness. Its fast and long-term effect has made it a people’s choice medicine for erectile dysfunction treatment all over the world. According to sociological studies, Cialis restores sexual health of 7 among 10 Frenchmen, the most affectionate men on the planet. The medicine leaves its competitors far behind and may be called an ideal remedy for sexual life correction. Cialis doesn’t require any restrictions: rationing, refuse of alcohol, driving, etc. There is no necessity in systematic intake – Cialis is important when it is needed.
Overdose
In case of one-time prescription of Cialis to sound men the tadalafil dosage equal to 500mg and to patients suffering from erectile dysfunction (many times up to 100mg a day), the side-effects were the same as occurred after the usage of smaller doses. In case of overdose, a standard expectant treatment should be undertaken. Tadalafil is practically not cleared with hemodialysis.
Special Note
Sexual activity has a potential risk for patients suffering from cardio-vascular diseases. Therefore, ED treatment including Cialis usage should not be conducted in men with cardiac failures, for whom the sexual intercourse is not recommended.
It should be taken into account that the potential risk of complications during sexual activity may occur in patients with the following diseases:
- myocardial infarction within the last 90 days;
- unstable angina or arrhythmia which may occur after sexual intercourse;
- cardiac failure of 2 class and higher according to NYHA within the last 6 months;
- uncontrolled heart beat disorders, hypotony or uncontrolled arterial hypertension;
- heart attack within the last six months.
Cialis should be taken with care by patients with underlying risk for priapism (sickle cell disease, erythroid myeloma, leukemia) or penis deformation (angulation, cavernosal fibrosis, Peyronie's disease). Priapism was reported while using of PDE5 inhibitors including tadalafil. Patients should be informed of the necessity of instant consultation by a specialist in case pf erection lasting four hours and more. Untimely treatment of priapism leads to penis tissues distortion. This condition may result in long-term potency loss.
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