Erectile dysfunction is becoming one of the urgent problems of modern men. The sexual disorders can be caused by both physiological and psychological factors; moreover there is a great deal of mixed forms of sexual disorders. Modern pharmacology has managed to meet the challenges of the present-day problems by issuing PDE5 inhibitors that are successfully applied for the treatment of erectile disorders. The most marketed PDE5 inhibitor is known to be Viagra (the trading name of Sildenafil), the branded product introduced at the market in 1998. Since then the given medication together with its multiple generic versions have become the most popular ED treatment medicines.
The mechanism of Erectile Dysfunction treatment
PDE5 inhibitors facilitate the relaxation of plain muscles of cavernous body of the penis. Due to that increased blood flow is achieved and stable and long-standing erection is maintained. Viagra works only in case of sexual excitement and does not treat the reason of the erectile disorder. It affects the natural mechanisms and does not build up a tolerance. Viagra should be taken once a day 40-60 minutes before the coitus. It is necessary that the man does not eat heavy or fat food as well as drink alcohol as all these factors slow down the action of the drug. Generic versions of Viagra allow small quantities of alcohol however admit that it is much better to refrain from drinking while taking ED treatment pills.
The average prescribed dose of Viagra is 50 mg of Sildenafil per day. The dose can be decreased to 25 mg if the man is over 65 or has serious health disorders that require complex treatment and careful prescription of other medical drugs. The dose of Sildenafil can be increased in case if no positive effect is achieved. However, the maximal daily dose should not be more than 100 mg. Viagra is not allowed for children under 18 and adult man who suffers from various disorders of cardio-vascular and gastrointestinal systems, heart and blood pressure problems as well as the physical deformity of penis. In general the complete list of diseases that are in the risk group is enclosed in every Viagra pack.
Viagra’s compatibility with other medications
As any other medication Sildenafil cannot be co-administered with certain medical drugs. Being very strong and effective substance Sildenafil is not prescribed with medications having the same influence on blood vessels. Among them one can name nitroglycerin and other nitrates. Being taken together Sildenafil and nitrates may cause significant drop of blood pressure, increased heart rate and chest pain. Sildenafil together with alpha blockers that are aimed at treating the prostate disorders may also predispose the sudden blood pressure drop.
Viagra is not co-administered with antibiotics such as erythromycin and others as well as with antifungal drugs like fluconazole and ketoconazole. These drugs usually slow down the performance of Sildenafil.
Sildenafil is not prescribed together with the similar PDE5 inhibitors such as Vardenafil (Levitra) and Tadalafil (Cialis).
Special attention should be paid while prescribing Sildenafil for men who are taking seizures treatment drugs (phenobarbital etc.) as well as medications for the heart rhythm control (sotalol) and antidepressants (fluoxetine and others).
In order to avoid undesirable side effects and deterioration of the human health doctors recommend that the patients inform about any medicine they take regularly. Moreover, in the medical insert to Viagra patients are provided with the complete list of drugs which are not co-administered with Sildenafil.
Know more about Vardenafil (Levitra) and Tadalafil (Cialis) in this articles:
http://www.mycanadianpharmacyrx.com/generic-levitra
https://www.drugs.com/cialis.html
www.canadahealthcaremall.com - Canadian Pharmacy Group
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